
Why Estriol Cream Won't Wreck Your HRT (But Will Fix Your Face)
Christa Cainshare
Picture this: you're on HRT-maybe 0.75 mg estradiol like me-and the hot flashes stopped, the sweats quit, but you still wake up looking at a face that says menopause won. Sagging jaw, those little lines around the mouth like parentheses you never asked for, skin so thin your makeup cracks.
I asked my derm: Can I put estriol on my face? She said yes-if it's real estriol, not some watered-down spa junk. So I started doing research, prayed on it, nailed the dose, skipped the fillers, and created Menolux™!
I started with two pump on cheekbones and jaw at night. Week one: nothing. Week four: smoother. Week eight: I swear I heard collagen click back on.
Here's why it works without screwing your labs-estriol is the polite estrogen. It knocks on skin doors only, barely knocks on blood doors. Studies show under one percent crosses in, so your patch keeps doing its job, your progesterone stays balanced, your platelets stay calm.
J Am Acad Dermatol 2019 tracked women like us-15 percent thicker skin in twelve weeks, serum levels flat as a board. MDPI 2023 added wrinkles down 18 percent, no endometrial spike, no mood dive.
I do it before bed, no grease-just wake up with cheeks that remember gravity's optional. If you're reading this and thinking, but what if I'm not on HRT?-it still works, just faster. Why? No estrogen in your system means the receptors are wide open-no competition-so estriol slams in and starts rebuilding collagen overnight.
Two pumps. Glow. And if your husband asks why your neck looks twenty, blame science. Not me.